Gene name:
MOBKL1A (MOB4A) ;
Protein name:
Mps one binder kinase activator-like 1A ;
Alternative:
Mob1B ;Mob1 homolog 1A (Mob1A) ;Protein Mob4A ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Binds STK38L. Interacts with LATS1 and LATS2.
Function:
Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L.
Subcellular Location:
Cytoplasm
Nucleus
Protein Attributes:
50:
MSFLFGSRSS | KTFKPKKNIP | EGSHQYELLK | HAEATLGSGN | LRMAVMLPEG |
100:
EDLNEWVAVN | TVDFFNQINM | LYGTITDFCT | EESCPVMSAG | PKYEYHWADG |
150:
TNIKKPIKCS | APKYIDYLMT | WVQDQLDDET | LFPSKIGVPF | PKNFMSVAKT |
200:
ILKRLFRVYA | HIYHQHFDPV | IQLQEEAHLN | TSFKHFIFFV | QEFNLIDRRE |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human Mps one binder kinase activator-like 1A
ELISA Kit for Human Mps one binder kinase activator-like 1A
CLIA Kit for Human Mps one binder kinase activator-like 1A
CLIA Kit for Human Mps one binder kinase activator-like 1A
Polyclonal Antibody for Human Mps one binder kinase activator-like 1A
Polyclonal Antibody for Human Mps one binder kinase activator-like 1A
Monoclonal Antibody for Human Mps one binder kinase activator-like 1A
Monoclonal Antibody for Human Mps one binder kinase activator-like 1A
Protein for Human Mps one binder kinase activator-like 1A
Protein for Human Mps one binder kinase activator-like 1A
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.